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반복 자연유산아의 융모막융모세포를 이용한 염색체 분석

Chromosomal Analysis of Abortus Chorionic Villi in Case or Recurrent Sponataneous Abortions

대한산부인과학회지 1993년 36권 12호 p.3897 ~ 3904
황혜란
서성숙/이신영/김정혜/박숙자

Abstract


Chromosomal analysis was done on abortus chorionic villi samples obtained 30 women with a history of two or more spontaneous abortions who were treated at Il Sin Christian Hospital between March 1992 and January 1993.
1. The overall incidence of chromosomal abnormalities was 36.7% (11 out of 30 cases).
2. Numerical abnormalities were detected in 9 women: 3 cases of monosomy(27.3%), 3 or trisomy (27.3%) and 3 of triploidy(27.3%).
Structural abnormalities were present 2 women, one case of inversion(9.1%) and one case of deletion(9.1%).
3. No abnormalities were detected in the remaining 19 women and there was no difference between those with normal and abnormal results in regard to age, number of abortions and abortus gestational age.

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