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유두양 장액성 자궁내막선암 2예

Two Cases of Uterine Papillary Serous Carcinoma

대한산부인과학회지 2004년 47권 12호 p.2499 ~ 2505
김주경/Kim JK
장보승/김승찬/윤영은/박옥랑/손경락/Chang BS/Kim SC/Yun YE/Park OR/Son KR

Abstract


Uterine papillary serous carcinoma (UPSC) behave more aggressively than other endometrial carcinomas and have a propensity for intraabdominal spread, simulating the behavior of ovarian carcinoma. Because of high relapsing rate, and high mortality rate of UPSC, many gynecologist studied about its treatment regimen and recommended many treatment method. Many investigators recommended that patients with UPSC should undergo a staging laparotomy and they suggested the surgery should include at least total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic lymphadenectomy, paraaortic lymphadenectomy, peritoneal washing and peritoneal cytology, By and large, adjuvant systemic Platinum based chemotherapy or, paclitaxel based chemotherapy and adjuvant whole abdominal irradiation or pelvic irradiation was prescribed. We experienced two cases of the UPSC stage IIIc and stage IV diagnosed after explolaparotomy. We present these cases and review the literatures about the optimal treatment regimen of UPSC.

키워드

UPSC;Laparotomy;Chemotherapy;Irradiation;유두양 장액성 자궁 내막선암;분자 유전학;시험 개복술;항암제;방사선치료
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