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BRCA1-mutated ovarian cancer with skin metastasis: a case report

대한산부인과학회지 2017년 60권 5호 p.477 ~ 480
 ( Oh So-Ra ) - Dong-A University College of Medicine Department of Obstetrics and Gynecology

 ( Park Jung-Woo ) - Dong-A University College of Medicine Department of Obstetrics and Gynecology
 ( Kwon Hyun-Young ) - Dong-A University College of Medicine Department of Obstetrics and Gynecology
 ( Rha Seo-Hee ) - Dong-A University College of Medicine Department of Pathology

Abstract


The major risk factor for ovarian cancer (OC) is mutation of the BRCA1 or BRCA2 DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that BRCA1- and BRCA2-mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of BRCA-mutated OCs is limited. Herein, we describe a case of OC with a BRCA1 mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.

키워드

Skin metastases; Ovarian neoplasms; BRCA mutation
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