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KMID : 0360220180590040362
대한안과학회지
2018년 59권 4호 p.362 ~ p.368
원발개방각녹내장 환자에서 섬유주절제술 후 점안 스테로이드 치료 효과 비교
Comparison of the Efficacy of Topical Steroids after Trabeculectomy in Patients with Primary Open-angle Glaucoma
하준영 ( Ha Jun-Young ) - 전남대학교 의과대학 안과학교실

이태희 ( Lee Tae-Hee ) - 전남대학교 의과대학 안과학교실
성미선 ( Sung Mi-Sun ) - 전남대학교 의과대학 안과학교실
박상우 ( Park Sang-Woo ) - 전남대학교 의과대학 안과학교실
- Abstract -
Purpose: To compare the surgical outcomes and intraocular pressure (IOP) reduction after trabeculectomy in patients with primary open-angle glaucoma (POAG) according to treatment with three different postoperative topical steroids.

Methods: A total of 84 eyes of 84 patients who had undergone trabeculectomy for POAG and were followed-up at least 1 year were included in this study. According to the postoperative topical steroid treatment, the patients were divided into three groups involving 0.5% loteprednol etabonate (LE), 1% rimexolone (RMX), and 1% prednisolone acetate (PDA). The mean IOP change, mean number of topical anti-glaucoma medication changes, 1-year success rate, and complication percentage were compared among the three groups.

Results: There were significant reductions in the IOP and number of anti-glaucoma medications during the postoperative 1-year follow-up in all of the groups (all, p < 0.05), but there were no differences among the three groups. Postoperative 1-year success rates (68.2% in the LE group, 67.0% in the RMX group, and 65.9% in the PDA group; p = 0.88) and complication percentages of trabeculectomy were not significantly different among the three groups.

Conclusions: There were no statistical differences in the 1-year success rate, complication percentage, visual acuity, IOP, and number of anti-glaucoma medications among treatment regimens. LE and RMX were as effective and safe as PDA after trabeculectomy in patients with POAG.
- Key Words -

Primary open-angle glaucoma, Topical steroid, Trabeculectomy
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