오늘 하루동안 보지 않기
잠시만 기다려 주세요. 로딩중입니다.

치매와 구강 건강의 관계

Association between dementia and oral health

대한치과의사협회지 2018년 56권 4호 p.218 ~ 230
KMID : 0362720180560040218
강경리 ( Kang Kyung-Lhi ) - 경희대학교 치의학전문대학원 치주과학교실

Abstract

According to the burst of aged people, researchers have focused on aging-related diseases. Cognitive impairment including Alzheimer’s disease (AD), one of the representative diseases related to aging, has no treatment option until now. Recently, it has been revealed that systemic inflammation plays a fundamental role in the pathogenesis of AD. Previous studies have suggested the association between poor oral health and cognitive impairment. Poor oral health can cause dental caries, chronic periodontitis, multiple tooth loss, and poor chewing ability, etc. Especially, periodontitis is a well-known chronic inflammatory disease and affects cognitive impairment directly and indirectly by inflammatory products mediators. Therefore, reduction of pathogenic microbial burden and inflammatory products by treating periodontitis can be a therapeutic modality to prevent cognitive impairment or to slow down the progression of it. Future studies are necessary to elucidate the causal relations and plausible mechanisms between poor oral health and cognitive impairment.
KeyWords

Alzheimer’s Disease, Dementia, Oral health
원문 및 링크아웃 정보
등재저널 정보
학술진흥재단(KCI)