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Current Stem Cell Therapy for Osteoarthritis

대한내과학회지 2019년 94권 2호 p.145 ~ 151
남유준 ( Nam Yoo-Jun ) - 가톨릭대학교 의과대학 내과학교실 류마티스내과

임예리 ( Rim Ye-Ri ) - 가톨릭대학교 의과대학 내과학교실 류마티스내과
임예리 ( Rim Ye-Ri ) - 가톨릭대학교 의과대학 내과학교실 류마티스내과
주지현 ( Ju Ji-Hyeon ) - 가톨릭대학교 의과대학 내과학교실 류마티스내과

Abstract

Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician’s office. There is a growing need, therefore, for physicians to pay attention to this common orthopedic condition. Cartilage degeneration, arthritic pain, and joint dysfunction are major manifestations of osteoarthritis, and degenerated cartilage is difficult to repair with conventional treatment modalities. Scientists and physicians have developed various therapeutic strategies, including the use of stem cells. Here, we discuss previous and current progress in cartilage regenerative therapy against osteoarthritis.

키워드

Osteoarthritis; Cartilage; Adult stem cells; Induced pluripotent stem cells; Chondrogenesis
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