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카바페넴 내성 장내세균: 감염 관리를 위한 신속한 검사실 진단 및 감시 배양

Carbapenem-Resistant Enterobacteriaceae: Rapid Laboratory Diagnosis and Surveillance Culture for Infection Control

대한내과학회지 2019년 94권 2호 p.170 ~ 172
우광숙 ( Woo Kwang-Sook ) - 동아대학교 의과대학 진단검사의학교실

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are increasing rapidly worldwide and in South Korea, which is a major problem for patient treatment and infection control. CRE is mainly due to carbapenem-hydrolyzing β-lactamase, which spreads through genetic mobile elements. Therefore, the rapid detection of carbapenemase-producing CRE (CP-CRE) and carrier surveillance are very important for infection control. Most clinical microbiology laboratories use automated real-time PCR methods for the rapid detection of CP-CRE; in some cases, additional accurate molecular tests are necessary. For the surveillance of risk groups, the complementary use of liquid culture and real-time PCR methods is important, taking into consideration their advantages and disadvantages. Furthermore, the expansion of surveillance targets is also necessary.

키워드

Carbapenem-resistant Enterobacteriaceae; Carbapenemase; Laboratory diagnosis; Surveillance culture
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