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Prognostic value of lymph node ratio in surgically treated cases of vulvar cancer: a tertiary care centre experience

Obstetrics & Gynecology Science 2020년 63권 2호 p.158 ~ 163
 ( Poddar Pabashi ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology

 ( Patel Shilpa ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology
 ( Arora Ruchi ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology
 ( Parekh Chetana ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology
 ( Dave Pariseema ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology
 ( Amin Sangeetha ) - Gujarat Cancer and Research Institute Department of Gynecological Oncology

Abstract


Objective: This study aimed to study the patterns of recurrence in surgically treated cases of vulvar cancer (VC) and determine the factors associated with recurrence, with a special emphasis on lymph node ratio (LNR).

Methods: This retrospective study examined VC patients primarily treated with surgery at our institute from January 2005 to December 2015. Demographic data, clinical characteristics, surgicohistopathological data, adjuvant treatment, follow up, and recurrence site and treatment were studied.

Results: Among the 111 cases treated, a recurrence rate of 18.9% was noted. Recurrence was most commonly local (61.9%). On univariate and multivariable analyses of clinicopathological parameters, an LNR >20 had the highest hazard ratio for recurrence.

Conclusion: LNR may provide useful prognostic information in VC patients with positive inguinal lymph node status.

키워드

Vulvar cancer; Lymph node ratio; Recurrence; Radiotherapy
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