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Late Onset Foreign Body Reaction due to Poly-L-Lactic Acid Facial Injections for Cosmetic Purpose

Annals of Dermatology 2020³â 32±Ç 6È£ p.519 ~ 522
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ÀüÀ¯Áø ( Jeon Yu-Jin ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology
±¸´ë¿ø ( Koo Dae-Won ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology
ÀÌÁ¾¼ø ( Lee Joong-Sun ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology

Abstract


The safety and efficacy of Poly-L-lactic acid (PLLA) as an injectable facial volumizer for the treatment of lipoatrophy and facial rejuvenation has been widely proven. We experienced a remarkable case of deep-seated nodules on both the cheeks of 57-year-old female 18-months after administration of PLLA filler injection for cosmetic purpose and performed a skin biopsy. With hematoxylin and eosin stain, the nodule showed non-caseating granulomas consisting of histiocytes with central foreign bodies in the dermis. This case report represents the late-onset foreign body reaction due to PLLA facial injections.

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Foreign-body reaction; Granuloma; Poly-L-lactic acid

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