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Late Onset Foreign Body Reaction due to Poly-L-Lactic Acid Facial Injections for Cosmetic Purpose

Annals of Dermatology 2020년 32권 6호 p.519 ~ 522
전유진, 구대원, 이종순,
소속 상세정보
전유진 ( Jeon Yu-Jin ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology
구대원 ( Koo Dae-Won ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology
이종순 ( Lee Joong-Sun ) - Eulji University School of Medicine Eulji University Hospital Department of Dermatology

Abstract


The safety and efficacy of Poly-L-lactic acid (PLLA) as an injectable facial volumizer for the treatment of lipoatrophy and facial rejuvenation has been widely proven. We experienced a remarkable case of deep-seated nodules on both the cheeks of 57-year-old female 18-months after administration of PLLA filler injection for cosmetic purpose and performed a skin biopsy. With hematoxylin and eosin stain, the nodule showed non-caseating granulomas consisting of histiocytes with central foreign bodies in the dermis. This case report represents the late-onset foreign body reaction due to PLLA facial injections.

키워드

Foreign-body reaction; Granuloma; Poly-L-lactic acid

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