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The pharmacological and biological roles of eriodictyol

Archives of Pharmacal Research 2020년 43권 6호 p.582 ~ 592
 ( Islam Anowarul ) - Chonbuk National University College of Veterinary Medicine

 ( Islam Md Sadikul ) - Chonbuk National University College of Veterinary Medicine
 ( Rahman Md Khalesur ) - Hajee Mohammad Danesh Science and Technology University Faculty of Veterinary and Animal Science Department of Microbiology
 ( Uddin Md Nazim ) - Sylhet Agricultural University Department of Livestock Production and Management
 ( Akanda Md Rashedunnabi ) - Sylhet Agricultural University Department of Pharmacology and Toxicology

Abstract


Eriodictyol is a flavonoid in the flavanones subclass. It is abundantly present in a wide range of medicinal plants, citrus fruits, and vegetables that are considered to have potential health importance. Having the considerable medicinal properties, eriodictyol has been predicted to clarify the mode of action in various cellular and molecular pathways. Evidence for the existing therapeutic roles of eriodictyol includes antioxidant, anti-inflammatory, anti-cancer, neuroprotective, cardioprotective, anti-diabetic, anti-obesity, hepatoprotective, and miscellaneous. Therefore, this review aims to present the recent evidence regarding the mechanisms of action of eriodictyol in different signaling pathways in a specific disease condition. In view of the immense therapeutic effects, eriodictyol may serve as a potential drug source to enhance community health standards.

키워드

Eriodictyol; Flavonoid; Therapeutic benefits; Oxidative stress; Health disorders
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