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A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance

Journal of Korean Medical Science 2020년 35권 24호 p.231 ~ 231
안병윤, 강창경, 서종도, 최평균, 송상훈, 박완범, 박상원, 김남중, 오명돈,
소속 상세정보
안병윤 ( Ahn Byeong-Yun ) - Seoul National University College of Medicine Department of Internal Medicine
강창경 ( Kang Chang-Kyung ) - Seoul National University College of Medicine Department of Internal Medicine
서종도 ( Seo Jong-Do ) - Seoul National University Hospital Department of Laboratory Medicine
최평균 ( Choe Pyoeng-Gyun ) - Seoul National University College of Medicine Department of Internal Medicine
송상훈 ( Song Sang-Hoon ) - Seoul National University Hospital Department of Laboratory Medicine
박완범 ( Park Wan-Beom ) - Seoul National University College of Medicine Department of Internal Medicine
박상원 ( Park Sang-Won ) - Seoul National University College of Medicine Department of Internal Medicine
김남중 ( Kim Nam-Joong ) - Seoul National University College of Medicine Department of Internal Medicine
오명돈 ( Oh Myoung-Don ) - Seoul National University College of Medicine Department of Internal Medicine

Abstract


There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.

키워드

COVID-19; SARS-CoV-2; Hydroxychloroquine; Prophylaxis

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