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Four cases of coronavirus disease 2019 in the early stage of pandemic of South Korea: a single public hospital experience

Korean Journal of Internal Medicine 2020년 35권 4호 p.788 ~ 792
안미영 ( Ahn Mi-Young ) - Seoul Medical Center Department of Internal Medicine

오동현 ( Oh Dong-Hyun ) - Seoul Medical Center Department of Internal Medicine
김수현 ( Kim Su-Hyun ) - Seoul Medical Center Department of Internal Medicine
최재필 ( Choi Jae-Phil ) - Seoul Medical Center Department of Internal Medicine
이지현 ( Lee Ji-Hyeon ) - Seoul Medical Center Department of Nursing
이영경 ( Lee Young-Kyung ) - Seoul Medical Center Department of Radiology
홍기호 ( Hong Ki-Ho ) - Seoul Medical Center Department of Laboratory Medicine

Abstract


In view of this pandemic, as of February 2020, South Korea has the second highest number of confirmed cases in the world. Herein, we report four confirmed coronavirus disease 2019 (COVID-19) cases in the early stage of the pandemic in South Korea and describe the identification, diagnosis, clinical course, and management, including one patient’s initial mild symptoms at presentation and their progression to pneumonia on day 21 of illness. Within 48 hours of hospitalization, all four patients underwent evaluation for initial laboratory parameters, COVID-19 polymerase chain reaction (PCR), and chest computed tomography (CT) findings. All four mild COVID-19 patients were discharged, and they were re-examined 14 days after discharge. Despite all four of them being asymptomatic, one patient was re-admitted after confirmation of COVID-19 through PCR viral nucleic acid detection. She could be discharged after 7 days with two subsequent negative COVID-19 PCR at 24-hour intervals. Patients with mild COVID-19 generally have normal follow-up chest CT scans after discharge, even if the early chest CT definitely indicates pneumonia. Re-hospitalized patients with COVID-19 PCR positive results after discharge were not related to her initial chest CT, lab, symptoms compared other three patients.

키워드

Coronavirus ; Pandemics ; Severe acute respiratory syndrome coronavirus 2
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