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Studies on Protein Synthesis of Maternal Liver and Fetus After Partial Hepatectomy

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Abstract


This study was undertaken to observe the interrelationship of protein synthesis between maternal regenerating liver and fetus by measuring the incorporation rate of L-lysine-C14.
In non-hepatectomized rats, the incorporation rate into plasma protein was faster in pregnant rats but no difference of the incorporation rate vas noted in other organs; regenerating liver, kidney, heart and adrenals, between pregnantand non-pregnant rats.
In hepatectomized rats (40 hrs. post-hepatectomy), the incorporation rate into liver proteir. revealed equally increased rate in non-pregnant and pregnant rats. The incorporation rate into protein of .intact fetus was rot influenced by partial hepatectomy but the number of fetal resorption ~Nas significantly increased in hepatectomized pregnant rats.

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