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색소피부건조증 환자에서 발생한 안면부 기저세포암의 치료 증례 보고

A Treatment of Basal cell Carcinoma on the Face of a Xeroderma Pigmentosum Patient: A Case Report

대한두경부종양학회지 2020년 36권 1호 p.39 ~ 44
배재현 ( Bae Jae-Hyun ) - Konkuk University Medical Center Department of Plastic and Reconstructive Surgery

 ( Jun Dong-Keun ) - Konkuk University Medical Center Department of Plastic and Reconstructive Surgery
김지남 ( Kim Jee-Nam ) - Konkuk University Medical Center Department of Plastic and Reconstructive Surgery
이명철 ( Lee Myung-Chul ) - Konkuk University Medical Center Department of Plastic and Reconstructive Surgery
신동혁 ( Shin Dong-Hyeok ) - Konkuk University Medical Center Department of Plastic and Reconstructive Surgery
임소덕 ( Lim So-Dug ) - Konkuk University Medical Center Department of Pathology
최현곤 ( Choi Hyun-Gon ) - Konkuk University School of Medicine Seoul Hospital Department of Plastic and Reconstructive Surgery

Abstract


Xeroderma pigmentosum is a rare autosomal recessive disease, related to defects in DNA repair mechanism. It presents skin lesions on sun-exposed areas, leading to various skin cancer. Skin lesions can be treated with cryotherapy, skin resurfacing, 5-FU, Imiquimod, topical T4 endonuclease V, radiotherapy and genetic therapy, but invasive skin cancer should be treated by a surgery. We report a 12-year-old female xeroderma pigmentosum patient with recurrent basal cell carcinoma successfully treated by skin grafting. In that there is no cure for this disease, prevention and patient education is most important.

키워드

Skin neoplasm; Xeroderma pigmentosum; Skin transplantation
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