잠시만 기다려 주세요. 로딩중입니다.

Topical agents: a thoughtful choice for multimodal analgesia

대한마취과학회지 2020년 73권 5호 p.384 ~ 393
최은주, 남상건, 한웅기, 이평복, 조지훈,
소속 상세정보
최은주 ( Choi Eun-Joo ) - Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine
남상건 ( Nahm Sahn-Gun ) - Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine
한웅기 ( Han Woong-Ki ) - Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine
이평복 ( Lee Pyung-Bok ) - Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine
조지훈 ( Jo Ji-Hun ) - Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine

Abstract


For over a thousand years, various substances have been applied to the skin to treat pain. Some of these substances have active ingredients that we still use today. However, some have been discontinued due to their harmful effect, while others have been long forgotten. Recent concerns regarding the cardiovascular and renal risk from nonsteroidal anti-inflammatory drugs, and issues with opioids, have resulted in increasing demand and attention to non-systemic topical alternatives. There is increasing evidence of the efficacy and safety of topical agents in pain control. Topical analgesics are great alternatives for pain management and are an essential part of multimodal analgesia. This review aims to describe essential aspects of topical drugs that physicians should consider in their practice as part of multimodal analgesia. This review describes the mechanism of popular topical analgesics and also introduces the most recently released and experimental topical medications.

키워드

Analgesia; Analgesics; Capsaicin; Cutaneous administration; Ketamine; Local anesthetics; Nonsteroidal anti-inflammatory agents; Opioids; Skin cream

원문 및 링크아웃 정보

 

등재저널 정보