잠시만 기다려 주세요. 로딩중입니다.

마이봄선기능장애 환자에서 안검미세각질제거의 임상효과

Clinical Efficacy of Microblepharoexfoliation in Meibomian Gland Dysfunction Patients

대한안과학회지 2020년 61권 6호 p.603 ~ 609
변형주 ( Byeon Hyeong-Ju ) - Yonsei University College of Medicine Department of Ophthalmology

전익현 ( Jun Ik-Hyun ) - Yonsei University College of Medicine Department of Ophthalmology
서경률 ( Seo Kyoung-Yul ) - Yonsei University College of Medicine Department of Ophthalmology
김응권 ( Kim Eung-Kweon ) - Yonsei University College of Medicine Department of Ophthalmology
김태임 ( Kim Tae-Im ) - Yonsei University College of Medicine Department of Ophthalmology

Abstract


Purpose: To assess the clinical efficacy of microblepharoexfolication using BlephEx™ (Scope Ophthalmics, London, UK) in meibomian gland dysfunction (MGD) patients.

Methods: We performed a prospective study involving 48 eyes of 24 patients who were diagnosed with MGD. All patients were treated with BlephEx™ for 8-10 minutes, and the ocular surface disease index (OSDI), tear break-up time (TBUT), Schirmer’s I test, corneal staining score, lid margin abnormality, MGD score, and lipid thickness layer using the Lipiview II (TearScience, Morrisville, NC, USA) were assessed before treatment and after one month.

Results: Significant changes were observed after microblepharoexfoliation using BlephExTM. The TBUT improved from 2.65 ± 1.16 to 3.77 ± 1.80 after 1 month (p < 0.001) and the OSDI improved from 38.83 ± 17.13 to 18.67 ± 15.01 after 1 month (p < 0.001). Before and after 1 month of treatment, the lid margin abnormalities were 2.98 ± 1.16 and 2.50 ± 1.01 (p < 0.001) and the MGD scores were 21.60 ± 6.95 and 18.02 ± 6.68 (p = 0.001), respectively.

Conclusions: BlephExTM improved the patients’ ocular surface symptoms, MGD score, and TBUT. Using steroid eye drops, there was a synergistic effect in improvement. Therefore, using BlephExTM may be suggested as a treatment option for MGD patients.

키워드

Biofilm; BlephExTM; Dry eye disease; Meibomian gland dysfunction; Microblepharoexfoliation
원문 및 링크아웃 정보
  
등재저널 정보
KCI
KoreaMed
KAMS