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비중격 천공에 의해 늦게 진단된 결절외 비성 Natural Killer/T 세포 림프종 1예

Delayed Diagnosis Due to Septal Perforation in Patient with Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type

대한이비인후과학회지-두경부외과학 2020년 63권 5호 p.223 ~ 227
이은수, 배우용, 이창배, 박민경,
소속 상세정보
이은수 ( Lee Eun-Soo ) - Dong-A University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
배우용 ( Bae Woo-Yong ) - Dong-A University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
이창배 ( Lee Chang-Bae ) - Dong-A University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
박민경 ( Park Min-Gyoung ) - Dong-A University College of Medicine Department of Pathology

Abstract


Extranodal natural killer (NK)/T-cell lymphoma, nasal type is a rare non-Hodgkin lymphoma originating in the nasal cavity or in the paranasal sinuses, and is etiologically closely related with the Epstein Barr Virus infection. It is more commonly found in East Asia, South America, and Mexico than in Europe or North America. Extranodal NK/T-cell lymphoma, nasal type typically shows a crust on the nasal mucosal surface, necrosis, and inflammation. Pathologically, it presents as significant vascular damage and destruction, with apparent tissue necrosis and cytotoxicity. These neoplasms are very aggressive and can show septal perforation, diffuse ulcer lesion on the nasal mucosa, fistula or epistaxis. We experienced a case of the extranodal NK/T-cell lymphoma, nasal type at the nasal septum, which was delayed in diagnosis due to septal perforation, which occurred after septoplasty in a 47-year-old female. Thus, we report this case with a review of literatures.

키워드

Nasal septal perforation; Lymphoma; extranodal NK-T-Cell; Surgery

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