잠시만 기다려 주세요. 로딩중입니다.

Successful combined second redo lungkidney transplantation in a patient who developed end-stage renal disease after a previous lung transplantation

대한이식학회지 2020년 34권 3호 p.193 ~ 198
노진희, 김도형, 조우현, 여혜주,
소속 상세정보
노진희 ( Noh Jin-Hee ) - Pusan National University Yangsan Hospital Department of Internal Medicine
김도형 ( Kim Do-Hyung ) - Pusan National University Yangsan Hospital Department of Thoracic and Cardiovascular Surgery
조우현 ( Cho Woo-Hyun ) - Pusan National University Yangsan Hospital Department of Internal Medicine
여혜주 ( Yeo Hye-Ju ) - Pusan National University Yangsan Hospital Department of Internal Medicine

Abstract


Several lung transplantation (LTx) patients develop end-stage renal disease (ESRD) and often need a kidney transplant. Recently, the number of multiorgan transplantation cases has increased; however, no successfully combined redo lung-kidney transplantation has been reported in Korea. We present the first case of combined second redo lung-kidney transplantation in a patient with ESRD after LTx. In November 2018, a 40-year-old man with dyspnea was admitted to our hospital. Seventeen years ago, he underwent right pneumonectomy owing to refractory extensive drug-resistant tuberculosis. Four years ago, he underwent left single-LTx due to chronic respiratory failure. He was diagnosed with chronic lung allograft dysfunction and ESRD (glomerular filtration rate, <15). He underwent a second LTx that resulted in acute graft failure. Despite the empirical management, he was not responsive to treatment. He was required to use a home ventilator, but was able to maintain good muscle strength and to walk. However, regular dialysis was required. In January 2019, he underwent combined second redo lung-kidney transplantation and was discharged. At 1-year follow-up, his pulmonary and renal functions were stable without rejection. Combined lung-kidney transplantation could be an effective treatment for selective young patients with respiratory and renal failure who have undergone LTx.

키워드

Lung transplantation; Kidney transplantation; Multiorgan transplantation

원문 및 링크아웃 정보

등재저널 정보