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數種앨러지性 皮膚疾患에 있어서 Immunoglobulins의 量的變化에 關한 硏究

Quantitative Changes of Immunoglobulin Levels in the Serum of Allergic Dermatoses Patients

대한피부과학회지 1969년 7권 1호 p.1 ~ 7
李鐘注, 金星煥, 林壽德,
소속 상세정보
李鐘注 (  ) - 서울대학교 醫科大學 皮膚科學敎室
金星煥 (  ) - 서울대학교 醫科大學 皮膚科學敎室
林壽德 (  ) - 서울대학교 醫科大學 皮膚科學敎室

Abstract


With development of immunochemical methods for analysis of serum proteins, quantitative determination of serum immunoglobulm levels and purification of them have been made passible in recent years.
There are numerous reports about immunoglobulm levels in various disc.
A search of the literature reveals very few reports of quantitative immunoglobulin determinations in allergic dermatoses.
The present study was conducted to find quantitative change of serum immunoglobulings in a few allergic dermatoses.
To quantify the Imo, IgA and IgM, one hundred and two sera were analysed from 30 normal control group, 30 contact dermatitis patients, 12 atopic dermatitis patients and 30 urticaria patients by modified Oudin´s capillary tube method.
The results are as follows.
1. In contact dermatitis the IgG was significantly increased to compare with control group (p<0. 01).
2. In atopic dermatitis the IgA was significantly increased to compare with control group (p<0.01) .
3. In urticaria the IgG was increased (p <0.05) .
4. The IgM has no differences between allergic dermatoses and control group.

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