잠시만 기다려 주세요. 로딩중입니다.

안면부 대상포진의 임상적 특징에 따른 안과적 합병증과 포진 후 신경통의 위험인자 분석

Clinical Features and Risk Factors of Facial Herpes Zoster: Ocular Complications and Postherpetic Neuralgia

대한피부과학회지 2020년 58권 4호 p.245 ~ 253
정한힘, 오신엽, 이현주, 허은필, 고재완,
소속 상세정보
정한힘 ( Jeong Han-Him ) - Sungkyunkwan University Samsung Changwon Hospital Department of Dermatology
오신엽 ( Oh Shin-Yeop ) - Sungkyunkwan University School of Medicine Samsung Changwon Hospital Department of Ophthalmology
이현주 ( Lee Hyun-Joo ) - Sungkyunkwan University Samsung Changwon Hospital Department of Dermatology
허은필 ( Heo Eun-Phil ) - Sungkyunkwan University Samsung Changwon Hospital Department of Dermatology
고재완 ( Go Jae-Wan ) - Sungkyunkwan University Samsung Changwon Hospital Department of Dermatology

Abstract


Background: Facial herpes zoster can be accompanied by several complications. In particular, postherpetic neuralgia (PHN) and ocular complications (OCs) are relatively common. Both PHN and OC are of interest because they can lower the quality of life.

Objective: This study aimed to evaluate the clinical features of facial herpes zoster and to assess the risk factors of OCs and PHN.

Methods: We analyzed the medical records of 146 patients with facial herpes zoster from January 2014 to May 2019. We assessed the proportion of OCs and PHN in patients with facial herpes zoster according to several clinical factors, including age, sex, dermatomal distribution, delayed time to treatment, and associated systemic conditions.
OCs were divided into mild and severe ocular complications (SOC) by ophthalmologic diagnosis.

Results: The incidence rate of OCs (83.8%) and SOC (37.8%) were highest in patients in their 70s. Herpes zoster involving the ophthalmic and maxillary branches of the trigeminal nerves showed a significantly higher incidence rate of OCs and SOC than those involving only the ophthalmic branch (p=0.031, p=0.025). Patients who received antiviral treatment within 4 days showed lower rates of OCs and SOC than patients who received treatment after 5 days (p<0.001, p=0.003). The incidence of PHN was significantly higher in those over 60 years old, when both the ophthalmic and maxillary branches were involved, and for those treated more than 4 days after the onset.

Conclusion: To decrease the risk of OCs and PHN in facial herpes zoster, it is important to provide early antiviral treatment and appropriate ophthalmologic consultation.

키워드

Facial herpes zoster; Ocular complications; Postherpetic neuralgia

원문 및 링크아웃 정보

등재저널 정보

KCI
KoreaMed
KAMS