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Clinical Factors for the Differential Diagnosis of Verruca Plana on the Head and Neck: A Study of Biopsy-proven Cases

대한피부과학회지 2020년 58권 8호 p.512 ~ 515
최성준, 윤현선,
소속 상세정보
최성준 ( Choi Sung-Jun ) - Seoul National University Hospital Department of Dermatology
윤현선 ( Yoon Hyun-Sun ) - SMG-SNU Boramae Medical Center Department of Dermatology

Abstract


Background: Both verruca plana (VP) and seborrheic keratosis (SK) cause a major cosmetic concern. However, it is difficult to discriminate VP from SK presenting multiple tiny papules, especially those located on the face and neck. As VP and SK have different treatment strategies and prognoses, differentiation between them is important.

Objective: The objective of this study was to elucidate the clinical differential characteristics between VP and VP-like SK on the face and neck.

Methods: We retrospectively investigated patients who underwent skin biopsy for differentiating between VP and VP-like SK. Multivariable logistic regression analysis was conducted to identify factors associated with the differential diagnosis.

Results: Among 80 identified cases, 48.7% (n=39) was VP, and 51.3% (n=41) was VP-like SK. In the multivariable logistic regression analysis, larger than 3-mm, skin-like or pink lesion color, and confluent distribution were more likely to indicate VP than VP-like SK.

Conclusion: Our study proposed useful clinical differential characteristics between VP and VP-like SK on the face and neck in a large number of biopsy-proven cases. Still, there are exceptions. Therefore, in such confusing cases, skin biopsy to attain exact diagnosis is recommended.

키워드

Differential diagnosis; Seborrheic keratosis; Warts

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