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재발 진행성 위암 환자의 FOLFOX 유발 부작용 개선에 대한 한의 치료 1례

A Case Report of FOLFOX-induced Adverse Events in a Patient with Recurrent Advanced Gastric Cancer Treated with Korean Medicine

대한한방내과학회지 2020년 41권 1호 p.81 ~ 87
고명현, 양재호, 전형준, 조종관, 이연월, 박소정, 유화승,
소속 상세정보
고명현 ( Ko Myung-Hyun ) - Daejeon University Dunsan Korean Medicine Hospital East West Cancer Center
양재호 ( Yang Jae-Ho ) - Daejeon University Dunsan Korean Medicine Hospital East West Cancer Center
전형준 ( Jeon Hyung-Joon ) - Daejeon University Seoul Korean Medicine Hospital East West Cancer Center
조종관 ( Cho Chong-Kwan ) - Daejeon University Dunsan Korean Medical Hospital East-West Cancer Center
이연월 ( Lee Yeon-Weol ) - Daejeon University Dunsan Korean Medical Hospital East-West Cancer Center
박소정 ( Park So-Jung ) - Daejeon University Dunsan Korean Medicine Hospital East West Cancer Center
유화승 ( Yoo Hwa-Seung ) - Daejeon University Seoul Korean Medicine Hospital East West Cancer Center

Abstract


Objective: The purpose of this study was to report the clinical effectiveness of Korean medicine treatment on FOLFOX-induced symptoms such as nausea and dizziness in a patient with recurrent advanced gastric adenocarcinoma.

Methods: The patient was diagnosed with recurrent advanced gastric cancer and had FOLFOX-induced nausea and dizziness. The patient was treated with Samchulgunbi-tang and Banhasashim-tang for symptom management. The clinical outcomes were measured by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI CTCAE) and a numeral rating scale (NRS).

Results: After treatment, the patient's nausea and dizziness were relieved from NRS 9 to 2 and NRS 8 to 2 respectively. During and after treatment, no severe toxicities were detected on laboratory findings.

Conclusion: This case study suggests that Samchulgunbi-tang and Banhasashim-tang may relieve symptoms of FOLFOX-induced nausea and dizziness.

키워드

advanced gastric cancer; adenocarcinoma; Korean medicine; quality of life; nausea; dizziness

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