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Dissimilarity between Human and Bacterial DNA

한국동물학회지 1968년 11권 3호 p.83 ~ 84
박인원,
소속 상세정보
박인원 ( Park In-Won ) - Seoul National University Department of Chemistry

Abstract


An attempt was made to estimate the possible homology between human and bacterial DNA by the method of DNA-agar gel hybridization. HeLa DNA was embedded in the agar and 14C-DNA Xanthomonas pelargonii was used as bacterial DNA for the sheared fragments. No homology between human and bacterial DNA was detected. If homology exists at all, it can be estimated from the sensitivity of the method and assuming some 1,000 nucleotide pairs per cistron, the not more than 2x10^5 base pairs or 200 bacterial cistrons would be preserved in human DNA, corresponding to less than 0.01 per cent of the total human genome.

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