잠시만 기다려 주세요. 로딩중입니다.

Catheter Ablation for Brugada Syndrome

Korean Circulation Journal 2020년 50권 4호 p.289 ~ 301
 ( Talib Ahmed Karim ) - University of Tsukuba Faculty of Medicine Department of Cardiology

 ( Nogami Akihiko ) - University of Tsukuba Faculty of Medicine Department of Cardiology

Abstract


Brugada syndrome (BrS) is an arrhythmogenic disease associated with an increased risk of ventricular fibrillation (VF) and sudden cardiac death (SCD). To date, the standard therapy for the prevention of SCD in BrS is the use of an implantable cardioverter-defibrillator (ICD) especially in patients who have experienced a prior cardiac arrest or syncopal events secondary to VF. However, ICDs do not prevent the occurrence of VF but react to defibrillate the VF episode, thereby preventing SCD. Often patients with recurrent VF have to be maintained on antiarrhythmic drugs that are effective but have remarkable adverse effects. An alternative therapy for BrS with recurrent VF is catheter ablation which emerged as an effective therapy in eliminating VF-triggering premature ventricular complexes in limited case series; however, there has been a remarkable progress in effectiveness of catheter ablation since epicardial substrate ablation was first applied in 2011 and such approach is now widely applicable.

키워드

Brugada syndrome; Ventricular fibrillation; Radiofrequency ablation; VF-trigger; Substrate
원문 및 링크아웃 정보
  
등재저널 정보