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리포솜 이중층의 stigmasterol이 포집된 ascorbic acid의 안정성에 미치는 영향

Effect of stigmasterol in liposome bilayer on the stabilization of encapsulated ascorbic acid

한국식품과학회지 2020년 52권 2호 p.200 ~ 203
이동욱 ( Lee Dong-Uk ) - Kyungnam University School of Bioconvergence

박혜원 ( Park Hye-Won ) - Kyungnam University School of Bioconvergence
이영경 ( Lee Seung-Cheol ) - Kyungnam University School of Bioconvergence

Abstract


The effect of stigmasterol (SS), a phytosterol, in the liposome bilayer on the stability of encapsulated ascorbic acid (ASA) was evaluated. Liposomes, consisting of phosphatidylcholine (PC) and SS, and ASA were encapsulated by the dehydration/rehydration method. The average particle size of the liposome increased with increasing SS content. SS significantly increased the stability of encapsulated ASA. For example, ASA remaining in the liposomes of 100:0, 90:10, and 70:30 (PC:SS, w/w) ratios was 34.12%, 49.88%, and 58.58%, respectively, after storage for 8 days at 4°C, while only 7.66% ASA remained in the buffer under the same conditions. These results indicated that SS in liposomes increased the stability of encapsulated ASA.

키워드

liposome; ascorbic acid; stigmasterol; stability
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