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초고령 환자에서 위의 위장관 기질 종양 수술 후 나타난 반복적인 문합부 재발

Gastric Gastrointestinal Stromal Tumor with Repeated Recurrence at the Anastomosis Site in a Very Elderly Patient

대한소화기학회지 2020년 76권 4호 p.206 ~ 210
김혜진, 박재용, 김범진, 김재규, 김희성, 박중민,
소속 상세정보
김혜진 ( Kim Hye-Jin ) - Chung-Ang University College of Medicine Department of Internal Medicine
박재용 ( Park Jae-Yong ) - Chung-Ang University College of Medicine Department of Internal Medicine
김범진 ( Kim Beom-Jin ) - Chung-Ang University College of Medicine Department of Internal Medicine
김재규 ( Kim Jae-Gyu ) - Chung-Ang University College of Medicine Department of Internal Medicine
김희성 ( Kim Hee-Sung ) - Chung-Ang University College of Medicine Department of Pathology
박중민 ( Park Joong-Min ) - Chung-Ang University College of Medicine Department of Surgery

Abstract


Although high-risk gastrointestinal stromal tumors (GISTs) frequently recur, even after a complete resection and imatinib therapy, local recurrence at the suture line after complete resection is rare. The present case was an 88-year-old woman who was initially diagnosed with high-risk GIST without a distant metastasis. She underwent a complete surgical resection of the lesion and received adjuvant imatinib therapy for 18 months, which was discontinued due to severe drug-induced anemia. During the follow- up, an endoscopic examination performed 40 months after the initial surgery revealed local recurrence at the anastomosis site. Although a complete surgical resection was performed, repeated local recurrence was detected 18 months later, which progressed rapidly to metastatic disease. This paper reports a case of a completely resected gastric GIST with repeated local recurrence, despite the complete surgical resections and adjuvant imatinib therapy.

키워드

Gastrointestinal stromal tumors; Surgery; Imatinib mesylate; Recurrence

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