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Prevalence and patient awareness of inflammatory bowel disease in Kazakhstan: a cross-sectional study

Intestinal Research 2020년 18권 4호 p.430 ~ 437
Kaibullayeva Jamilya, Ualiyeva Aliya, Oshibayeva Ainash, Dushpanova Anar, Marshall John K.,
소속 상세정보
 ( Kaibullayeva Jamilya ) - Research Institute of Cardiology and Internal Diseases Department of Gastroenterology and Hepatology
 ( Ualiyeva Aliya ) - Al-Farabi Kazakh National University Department of Epidemiology, Biostatistics and Evidence Based Medicine
 ( Oshibayeva Ainash ) - Al-Farabi Kazakh National University Department of Epidemiology, Biostatistics and Evidence Based Medicine
 ( Dushpanova Anar ) - Al-Farabi Kazakh National University Department of Epidemiology, Biostatistics and Evidence Based Medicine
 ( Marshall John K. ) - McMaster University Division of Gastroenterology

Abstract


Background/Aims: There has been a paucity of published data on the epidemiology of inflammatory bowel disease (IBD) in Central Asia and Kazakhstan. Therefore, we aimed to study IBD prevalence and patient awareness among adults in Kazakhstan.

Methods: The cross-sectional study was carried out among subjects of both sexes aged 18 years and older using IBD Alert Questionnaire (CalproQuest), single fecal calprotectin test, and endoscopy with biopsy to verify IBD from January to December 2017, across regions of Kazakhstan. All participants were included in the study after providing informed consent.

Results: Out of 115,556 subjects, there were 128 confirmed IBD cases, in which 36 Crohn’s disease (CD) and 92 ulcerative colitis (UC) cases identified. The age and sex-adjusted IBD prevalence were 113.9 (95% confidence interval [CI], 69.0?158.9) per 100,000 population. The age- and sex-adjusted prevalence for UC were 84.4 (95% CI, 44.8?123.9) and for CD were 29.5 (95% CI, 8.2?50.9) per 100,000 population.

Conclusions: This is the first report on the prevalence of IBD with a verified diagnosis in the Central Asia and could be used to better plan and allocate healthcare resources for IBD management program.

키워드

Inflammatory bowel diseases; Prevalence; Kazakhstan

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