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Psychological profiles of irritable bowel syndrome patients with different phenotypes

Intestinal Research 2020년 18권 4호 p.459 ~ 468
Bouchoucha Michel, Devroede Ghislain, Girault-Lidvan Noelle, Hejnar Maria, Mary Florence, Benamouzig Robert,
소속 상세정보
 ( Bouchoucha Michel ) - University Rene Descartes Department of Physiology
 ( Devroede Ghislain ) - University of Sherbrooke Faculty of Medicine and Health Sciences Department of Surgical
 ( Girault-Lidvan Noelle ) - University Rene Descartes Psychological Institute
 ( Hejnar Maria ) - Avicenne Hospital Psychiatry and Psychopathology Unit
 ( Mary Florence ) - Avicenne Hospital Department of Gastroenterology
 ( Benamouzig Robert ) - Avicenne Hospital Department of Gastroenterology

Abstract


Background/Aims: Abnormal psychological profiles are frequently found in patients with functional gastrointestinal disorders (FGIDs). The present study aimed to evaluate the psychological profiles of FGID patients with irritable bowel syndrome (IBS), and IBS phenotypes.

Methods: In 608 FGID patients, including 235 with IBS, have filled a Rome III questionnaire and the French version of the Minnesota Multiphasic Personality Inventory 2. Data analysis was performed using univariate analysis and multivariate logistic regression.

Results: This study shows that IBS patients have abnormal psychological profiles with more significant symptom exaggeration and decreased test defensiveness than non-IBS patients. They have a significantly higher score for all clinical scales. Logistic regression analysis showed in IBS patients a decrease of body mass index (P= 0.002), and test defensiveness score K (P= 0.001) and an increase of Hypochondriasis (P< 0.001) and Masculinity-Femininity scale (P= 0.018). By comparison with non-IBS patients, IBS-constipation, IBS-diarrhea, and mixed IBS patients have increased Hypochondriasis value and Depression score, mixed IBS patients have higher Psychasthenia score and higher Hypomania score. No item was significantly different in the IBS-unspecified group.

Conclusions: This study shows that IBS patients have different psychological profiles than other FGID patients and that psychological characteristics are associated with IBS phenotypes except for patients with unsubtyped IBS.

키워드

Irritable bowel syndrome; MMPI-2; Depression; Sex; Life stress events

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