잠시만 기다려 주세요. 로딩중입니다.

Influences of dietary flavonoid (quercetin) supplementation on growth performance and immune response of growing pigs challenged with Escherichia coli lipopolysaccharide

한국축산학회지 2020년 62권 5호 p.605 ~ 613
박재홍, Sureshkumar Shanmugam, 김인호,
소속 상세정보
박재홍 ( Park Jae-Hong ) - Dankook University Department of Animal Resource and Science
 ( Sureshkumar Shanmugam ) - Dankook University Department of Animal Resource and Science
김인호 ( Kim In-Ho ) - Dankook University Department of Animal Resource and Science

Abstract


This study was conducted to evaluate the effects of dietary supplementation of plant flavonoid (quercetin) on immune parameters, growth performance, and nutrient digestibility in growing pigs challenged with Escherichia coli lipopolysaccharide (LPS). A total of 40 crossbred ([Landrace × Yorkshire] × Duroc) growing pigs; initial body weight (BW) of 26.95 ± 1.26 kg were used in a six-week experimental trial. Pigs were randomly allocated into one of four treatment groups in a 2 × 2 factorial arrangement with the following factors; without LPS challenge and with LPS challenge (day 21) supplemented with or without 0.1% flavonoid according to BW (2 replicate pens per treatment with 2 gilts and 3 barrows per pen). The single- dose LPS (100 ug / kg BW) injection showed trends tended to be increased in interleukin-6 (IL-6) after 2 h and 6 h of challenge compared with unchallenged pigs. However, other measured immune indices (white blood cell, immunoglobulin G, lymphocyte, and tumor necrosis factor), growth performance, and nutrient digestibility were not significantly different between challenged and non-challenged animals. The supplementation of flavonoid significantly increased (p < 0.05) average daily gain (ADG) during day 0?21, tended to increase dry matter and nitrogen digestibility, significantly reduced IL-6, increased Ig-G and WBC concentrations and increased lymphocytes percentage regardless of LPS challenge.

키워드

Flavonoid; Growing pigs; Immune stimulation; Lipopolysaccharide

원문 및 링크아웃 정보

등재저널 정보