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Primary Gliosarcoma with Extracranial Metastasis

Brain Tumor Research and Treatment : BTRT 2020년 8권 1호 p.53 ~ 56
최민규, 이정호, 이민석, 서상준, 이윤수, 강동기,
소속 상세정보
최민규 ( Choi Min-Gyu ) - Daegu Fatima Hospital Department of Neurosurgery
이정호 ( Lee Jeong-Ho ) - Daegu Fatima Hospital Department of Neurosurgery
이민석 ( Lee Min-Seok ) - Daegu Fatima Hospital Department of Neurosurgery
서상준 ( Suh Sang-Jun ) - Daegu Fatima Hospital Department of Neurosurgery
이윤수 ( Lee Yoon-Soo ) - Daegu Fatima Hospital Department of Neurosurgery
강동기 ( Kang Dong-Gee ) - Daegu Fatima Hospital Department of Neurosurgery

Abstract


A 69-year-old male presented with a week of worsening headache, mild dizziness and left side weakness, and the radiological work-up of his brain displayed an enhancing mass on the right frontal lobe. The tumor was totally resected. The patient was initially diagnosed with glioblastoma multiforme. His neurologic symptoms recovered after surgery. He underwent adjuvant radiotherapy with concurrent temozolomide. Approximately 7 months after surgery, the patient complained of epigastric pains. Abdominal CT scan showed multiple hepatic metastasis and multiple lymphadenopathy. Chest CT and Torso positron emission tomography-CT scans for additional metastasis study revealed multiple metastatic lesions in the right lung, left pleura, liver, lymph nodes, bones, and muscles. Percutaneous liver biopsy was performed, and associated pathology was consistent with sarcomatous component. After liver biopsy, brain tumor pathology was reviewed, which revealed typical gliomatous and sarcomatous components. The patient was therefore diagnosed with metastatic gliosarcoma. The patient was in a septic condition with aggravated pleural effusion. The patient died 9 months after the diagnosis of primary gliosarcoma.

키워드

Brain tumor; Gliosarcoma; Glioblastoma

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