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Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Both the Nasal Cavity and the Cranial Cavity

Brain Tumor Research and Treatment : BTRT 2020년 8권 1호 p.57 ~ 61
Yoon Sang-Youl, 박기수, 황정현, 박성현, 한만훈,
소속 상세정보
 ( Yoon Sang-Youl ) - Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Neurosurgery
박기수 ( Park Ki-Su ) - Kyungpook National University School of Medicine Kyungpook National University Chilgok Hospital Department of Neurosurgery
황정현 ( Hwang Jeong-Hyun ) - Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Neurosurgery
박성현 ( Park Seong-Hyun ) - Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Neurosurgery
한만훈 ( Han Man-Hoon ) - Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Pathology

Abstract


Sinonasal teratocarcinosarcoma (SNTCS), a very rare tumor, is known to be a heterogeneous with epithelial, mesenchymal, and neuroepithelial components and shows a very aggressive clinical course. Due to the heterogeneity of this tumor, it is often misdiagnosed. No definitive treatment modality has been reported because it is a very rare tumor. A 44-year-old man presented to a rhinologist with headache and nasal obstruction, and an intranasal tumor was found that invaded into the cranial cavity. He underwent combined surgery with a rhinologist and a neurosurgeon following cognitive decline that worsened after a transnasal biopsy. The patient was diagnosed with SNTCS and underwent radiotherapy. However, residual tumor was found during radiotherapy and additional chemotherapy was administered. Follow-up brain MRI revealed no remnant or recurrent lesion. SNTCS is a tumor that has not yet been well researched and should be further investigated for proper treatment.

키워드

Teratocarcinosarcoma; Brain tumor; Chemotherapy; Radiotherapy

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