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Updates on bone health in children with gastrointestinal diseases

Annals of Pediatric Endocrinology & Metabolism 2020년 25권 1호 p.10 ~ 14
양혜란,
소속 상세정보
양혜란 ( Yang Hye-Ran ) - Seoul National University Bundang Hospital Department of Pediatrics

Abstract


Chronic gastrointestinal diseases such as inflammatory bowel disease, malabsorption syndromes (e.g., intestinal lymphangiectasia, celiac disease, congenital chloride diarrhea, cystic fibrosis), and postsubtotal gastrectomy state or short-bowel syndrome after extensive bowel resection are related to poor bone health in pediatric patients due to increased risks of low bone mineral density, osteoporosis, and fractures. The pathophysiology of abnormal bone health in pediatric gastrointestinal diseases may present from inflammation to malabsorption. In children with chronic gastrointestinal diseases at high risk of poor bone health, routine evaluation using dual-energy X-ray absorptiometry and appropriate prevention or treatment strategies are needed.

키워드

Bone mineral density; Gastrointestinal; Inflammatory bowel disease; Malabsorption; Short-bowel syndrome; Child

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