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Bone health in pediatric patients with neurological disorders

Annals of Pediatric Endocrinology & Metabolism 2020년 25권 1호 p.15 ~ 23
고아라, 공주현, Samadov Furkat, Mukhamedov Akmal, 김영미, 이윤진, 남상욱,
소속 상세정보
고아라 ( Ko A-Ra ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics
공주현 ( Kong Ju-Hyun ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics
 ( Samadov Furkat ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics
 ( Mukhamedov Akmal ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics
김영미 ( Kim Young-Mi ) - Pusan National University School of Medicine Pusan National University Hospital Department of Pediatrics
이윤진 ( Lee Yun-Jin ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics
남상욱 ( Nam Sang-Ook ) - Pusan National University School of Medicine Pusan National University Children’s Hospital Department of Pediatrics

Abstract


Patients with neurological disorders are at high risk of developing osteoporosis, as they possess multiple risk factors leading to low bone mineral density. Such factors include inactivity, decreased exposure to sunlight, poor nutrition, and the use of medication or treatment that can cause lower bone mineral density such as antiepileptic drugs, ketogenic diet, and glucocorticoids. In this article, mechanisms involved in altered bone health in children with neurological disorders and management for patients with epilepsy, cerebral palsy, and Duchenne muscular dystrophy regarding bone health are reviewed.

키워드

Osteoporosis; Bone; Neurological disorders; Child; Epilepsy; Cerebral palsy

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