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Comparison of Oral Sulfate Solution and Polyethylene Glycol Plus Ascorbic Acid on the Efficacy of Bowel Preparation

Clinical Endoscopy 2020년 53권 5호 p.568 ~ 574
남지형, 홍석보, 임윤정, 이승주, 강현우, 김재학, 이진호,
소속 상세정보
남지형 ( Nam Ji-Hyung ) - Dongguk University Ilsan Hospital Department of Internal Medicine
홍석보 ( Hong Seok-Bo ) - Dongguk University Ilsan Hospital Department of Internal Medicine
임윤정 ( Lim Yun-Jeong ) - Dongguk University Ilsan Hospital Department of Internal Medicine
이승주 ( Lee Seong-Ju ) - Dongguk University Ilsan Hospital Department of Internal Medicine
강현우 ( Kang Hyoun-Woo ) - Dongguk University Ilsan Hospital Department of Internal Medicine
김재학 ( Kim Jae-Hak ) - Dongguk University Ilsan Hospital Department of Internal Medicine
이진호 ( Lee Jin-Ho ) - Dongguk University Ilsan Hospital Department of Internal Medicine

Abstract


Background/Aims: The quality of bowel preparation is one of the quality indicators for colonoscopy. The aim of this study was to compare the efficacy of oral sulfate solution (OSS) and polyethylene glycol plus ascorbic acid (PEG-AA) for bowel preparation.

Methods: The study involved 167 patients who underwent diagnostic colonoscopies. Inadequate bowel preparation was defined as any score of ≤1 in each colon section based on the Boston Bowel Preparation Scale. Multivariate logistic regression was used to compare the efficacy of OSS and PEG-AA. Subgroup analyses were performed based on patient characteristics.

Results: Overall, 106 (63.5%) patients received OSS, and 61 (36.5%) patients received PEG-AA. The rate of inadequate bowel preparation was 12.3% in patients receiving OSS and 32.8% in patients receiving PEG-AA (p=0.001). OSS (odds ratio [OR] = 0.26; p=0.003) and morning examination (OR=0.11; p=0.038) were significantly associated with efficient bowel preparation. The efficacy of OSS compared with PEG-AA was only significant in patients ≥50 years of age vs. <50 years of age (OR=0.13; p=0.001 vs. OR=0.96; p=0.959) and female vs. male patients (OR=0.06; p=0.002 vs. OR=0.58; p=0.339).

Conclusions: OSS was significantly more efficient for bowel preparation than PEG-AA, especially in patients ≥50 years of age and female patients. Morning examination led to a good quality of bowel preparation, irrespective of the preparation regimen.

키워드

Bowel preparation; Colonoscopy; Oral sulfate solution; Polyethylene glycol

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