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Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography

Ultrasonography 2020년 39권 3호 p.229 ~ 237
Sugimoto Katsutoshi, Abe Masakazu, Yoshimasu Yu, Takeuchi Hirohito, Kasai Yoshitaka, Itoi Takao,
소속 상세정보
 ( Sugimoto Katsutoshi ) - Tokyo Medical University Department of Gastroentelorogy and Hepatology
 ( Abe Masakazu ) - Tokyo Medical University Department of Gastroentelorogy and Hepatology
 ( Yoshimasu Yu ) - Tokyo Medical University Department of Gastroentelorogy and Hepatology
 ( Takeuchi Hirohito ) - Tokyo Medical University Department of Gastroentelorogy and Hepatology
 ( Kasai Yoshitaka ) - Tokyo Medical University Department of Gastroentelorogy and Hepatology
 ( Itoi Takao ) - Tokyo Medical University Department of Gastroenterology and Hepatology

Abstract


Irreversible electroporation (IRE) is a novel form of soft tissue ablation therapy that uses high-current electrical pulses to induce the formation of pores in the cell membrane, leading to cell death. Although outcome data for the ablation of hepatocellular carcinoma (HCC) by IRE are limited, early results are encouraging and may suggest equivalency to the outcomes achieved by thermal ablation methods such as radiofrequency ablation (RFA) and microwave ablation (MWA). However, IRE can be a challenging and very time-consuming procedure compared to RFA and MWA. In this review article, we not only evaluate the efficacy and safety of IRE for the treatment of HCC, but also discuss imaging guidance, ablation monitoring, and endpoint assessment, with a particular focus on ultrasonography.

키워드

Irreversible electroporation; Hepatocellular carcinoma; Ultrasonography; Ablation

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