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Major enteropathogens in humans, domestic animals, and environmental soil samples from the same locality: prevalence and transmission considerations in coastal Odisha, India

Epidemiology and Health 2020년 42권 1호 p.34 ~ 34
Shrivastava Arpit Kumar, Mohakud Nirmal Kumar, Panda Swagatika, Patra Saumya Darshana, Kumar Subrat, Sahu Priyadarshi Soumyaranjan,
소속 상세정보
 ( Shrivastava Arpit Kumar ) - Kalinga Institute of Industrial Technology University School of Biotechnology Infection Biology Laboratory
 ( Mohakud Nirmal Kumar ) - Kalinga Institute of Industrial Technology University Kalinga Institute of Medical Sciences
 ( Panda Swagatika ) - Kalinga Institute of Industrial Technology University School of Biotechnology Infection Biology Laboratory
 ( Patra Saumya Darshana ) - Kalinga Institute of Industrial Technology University School of Biotechnology Infection Biology Laboratory
 ( Kumar Subrat ) - Kalinga Institute of Industrial Technology University School of Biotechnology Infection Biology Laboratory
 ( Sahu Priyadarshi Soumyaranjan ) - Kalinga Institute of Industrial Technology University School of Biotechnology Infection Biology Laboratory

Abstract


Objectives: Regions with limited sanitation facilities have higher rates of infections with various enteric pathogens. It is therefore important to identify different hosts and their relative contribution to pathogen shedding into the environment, and to assess the subsequent health risks to humans.

Method: In this study, human faecal (n=310), animal faecal (n=150), and environmental (soil) samples (n=40) were collected from the same locality and screened for selected enteric pathogens by immunochromatography and/or polymerase chain reaction.

Results: At least 1 microbial agent was detected in 49.0%, 44.7%, and 40.0% of the samples from human, animals, and soil, respectively. Among humans, rotavirus was predominantly detected (17.4%) followed by enteropathogenic Escherichia coli (EPEC) (15.4%), Shigella (13.8), and Shiga toxin-producing E. coli (STEC) (9.7%). Among animals, STEC was detected most frequently (28.0%), and EPEC was the major enteric pathogen detected in soil (30.0%). The detection rate of rotavirus was higher among younger children (≤2 years) than among older children. Single infections were more commonly detected than multiple infections in humans (p<0.01), unlike the observations in animal and soil samples. For diarrhoeagenic E. coli and Shigella, most of the human and animal isolates showed close relatedness, suggesting possible cross-infection between humans and domesticated animals in the area studied.

Conclusions: The present study provides an improved understanding of the distribution of major enteric pathogens coexisting in humans and animals in the region, thereby suggesting a high potential for possible transmission among livestock and communities residing in the studied locality.

키워드

Diarrhoea; Molecular epidemiology; Coinfection; Zoonoses; India

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