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Huge Hepatocellular Carcinoma Exhibiting a Complete Response after Stereotactic Body Radiation Therapy

대한간암학회지 2020년 20권 2호 p.167 ~ 172
신경인, 장병국, 김진희, 황재석,
소속 상세정보
신경인 ( Shin Kyung-In ) - Keimyung University School of Medicine Department of Internal Medicine
장병국 ( Jang Byoung-Kuk ) - Keimyung University School of Medicine Department of Internal Medicine
김진희 ( Kim Jin-Hee ) - Keimyung University School of Medicine Department of Radiation Oncology
황재석 ( Hwang Jae-Seok ) - Keimyung University School of Medicine Department of Internal Medicine

Abstract


To date, there are limited data and little consensus on treatment strategies for huge hepatocellular carcinoma (HCC). Surgical resection provides significantly better survival than other modalities for single large HCC regardless of tumor stage. Recently, with technological advances in radiation therapy, stereotactic body radiation therapy (SBRT) is considered an alternative treatment option for HCC. Herein, we present a case of huge HCC that was successfully managed by SBRT. Transarterial embolization, previously performed in Russia, was incomplete. It was also not suitable for resection and transarterial chemoembolization. Although the rationale for radiotherapy in huge HCC was insufficient, SBRT was performed because no other treatment options were available. Additional radiofrequency ablation was performed for small HCC in a different segment, and radiological complete response (CR) was achieved. The CR was maintained over 4 years. Therefore, SBRT may be an alternative treatment option for large HCC that is not suitable for curative treatment.

키워드

Hepatocellular carcinoma; Stereotactic body radiotherapy

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