잠시만 기다려 주세요. 로딩중입니다.

Sarcoma metastasis to the pancreas: experience at a single institution

Journal of Pathology and Translational Medicine 2020년 54권 3호 p.220 ~ 227
이미선, 송준선, 홍승모, 장세진, 김지헌, 송기병, 이재훈, 조경자,
소속 상세정보
이미선 ( Lee Mi-Seon ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology
송준선 ( Song Joon-Seon ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology
홍승모 ( Hong Seung-Mo ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology
장세진 ( Jang Se-Jin ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology
김지헌 ( Kim Ji-Hun ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology
송기병 ( Song Ki-Byung ) - University of Ulsan College of Medicine Asan Medical Center Department of Surgery
이재훈 ( Lee Jae-Hoon ) - University of Ulsan College of Medicine Asan Medical Center Department of Surgery
조경자 ( Cho Kyung-Ja ) - University of Ulsan College of Medicine Asan Medical Center Department of Pathology

Abstract


Background: Reports of metastatic sarcoma to the pancreas are limited. We reviewed the clinicopathologic characteristics of such cases.

Methods: We reviewed 124 cases of metastatic tumors to the pancreas diagnosed at Asan Medical Center between 2000 and 2017.

Results: Metastatic tumors to the pancreas consisted of 111 carcinomas (89.5%), 12 sarcomas (9.6%), and one melanoma (0.8%). Primary sarcoma sites were bone (n=4); brain, lung, and soft tissue (n=2 for each); and the uterus and pulmonary vein (n=1 for each). Pathologically, the 12 sarcomas comprised 2 World Health Organization grade III solitary fibrous tumors/hemangiopericytomas, and one case each of synovial sarcoma, malignant solitary fibrous tumor, undifferentiated pleomorphic sarcoma, osteosarcoma, mesenchymal chondrosarcoma, intimal sarcoma, myxofibrosarcoma, myxoid liposarcoma, rhabdomyosarcoma, subtype uncertain, and high-grade spindle-cell sarcoma of uncertain type. The median interval between primary cancer diagnosis and pancreatic metastasis was 28.5 months. One case manifested as a solitary pancreatic osteosarcoma metastasis 15 months prior to detection of osteosarcoma in the femur and was initially misdiagnosed as sarcomatoid carcinoma of the pancreas.

Conclusions: The metastatic sarcoma should remain a differential diagnosis when spindle-cell malignancy is found in the pancreas, even for solitary lesions or in patients without prior history.

키워드

Pancreas; Metastasis; Sarcoma

원문 및 링크아웃 정보

 

등재저널 정보