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Pediatric granular cell tumor in the posterior wall of the larynx extending to the trachea

Journal of Pathology and Translational Medicine 2020년 54권 4호 p.336 ~ 339
Ahn Jung-Suk, 김나래, 선용한,
소속 상세정보
 ( Ahn Jung-Suk ) - Gachon University College of Medicine Gil Medical Center Department of Pathology
김나래 ( Kim Na-Rae ) - Gachon University College of Medicine Gil Medical Center Department of Pathology
선용한 ( Sun Yong-Han ) - Gachon University College of Medicine Gil Medical Center Department of Pediatrics

Abstract


Granular cell tumor (GCT) is a slow-growing benign neoplasm that can be found in any organ. Pediatric laryngotracheal GCT is rare. We experienced a 6-year-old boy suffering from a barking cough and symptoms of stridor and croup for one month. Head and neck computed tomography revealed a protruding mass that occluded 60% of the airway lumen. Under the impression of hemangioma or papilloma, excision revealed a submucosal non-encapsulated mass. Histologically, the mass was composed of sheets of large polyhedralshaped tumor cells containing plump eosinophilic granular cytoplasm and centrally placed, small, bland-appearing nuclei. The tumor cells were positive for S-100 protein, and voluminous eosinophilic cytoplasm was stained by diastase-resistant periodic acid-Schiff. The present report describes a unique case of a huge pediatric laryngeal GCT extending to the subglottic trachea. We also review the clinical course of pediatric laryngotracheal GCT and emphasize the importance of diagnosing GCT in children.

키워드

Granular cell tumor; Trachea; Larynx; Children

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