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The lymphatic system in alcohol-associated liver disease

Clinical and Molecular Hepatology 2020년 26권 4호 p.633 ~ 638
Kondo Reiichiro, Iwakiri Yasuko,
소속 상세정보
 ( Kondo Reiichiro ) - Yale University School of Medicine Department of Internal Medicine
 ( Iwakiri Yasuko ) - Yale University School of Medicine Department of Internal Medicine

Abstract


The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.

키워드

Lymphangiogenesis; Vascular endothelial growth factor C; Inflammation; Lymphatics

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