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Liver-lung axes in alcohol-related liver disease

Clinical and Molecular Hepatology 2020년 26권 4호 p.670 ~ 676
Arteel Gavin E.,
소속 상세정보
 ( Arteel Gavin E. ) - University of Pittsburgh Pittsburgh Liver Research Center Department of Medicine

Abstract


Alcohol-related liver disease (ALD) and alcohol-related susceptibility to acute lung injury are the leading causes of morbidity and mortality due to chronic alcohol abuse. Most commonly, alcohol-induced injury to both organs are evaluated independently, although they share many parallel mechanisms of injury. Moreover, recent studies indicate that there is a potential liver lung axis that may contribute to organ pathology. This mini-review explores established and potential mechanisms of organ-organ crosstalk in ALD and alcohol-related lung injury.

키워드

Liver diseases; Alcoholic Liver disease; Acute lung injury; Respiratory distress syndrome, Adult

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