Health-related Quality of Life of Children and Adolescents after Hematopoietic Stem Cell Transplantation
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ȲÀ¯¹Î ( Hwang Yu-Min ) - Seoul National University Hospital
¹æ°æ¼÷ ( Bang Kyung-Sook ) - Seoul National University College of Nursing
Abstract
Purpose: This study aimed to determine the level of health-related quality of life (HRQoL) of children and adolescents who received hematopoietic stem cell transplantation (HSCT) and to examine factors influencing HRQoL.
Methods: This cross-sectional descriptive study involved 85 participants aged 10 to 19 years who received treatment from 3 months to 5 years after HSCT. Symptom experiences, stress and coping, self-esteem, social support, and HRQoL were measured. Descriptive analysis, the independent t-test, one-way analysis of variance, Pearson correlation analysis, and stepwise multiple regression were used for data analysis.
Results: The mean HRQoL score was 72.26 points out of 100. HRQoL showed statistically significant correlations with symptom experiences, stress, self-esteem, social support, satisfaction with peer relationships, and perceived attentiveness of the medical team. The most influential predictors of HRQoL were symptom experiences (¥â=-.51, p<.001) and satisfaction with peer relationships (¥â=.32, p<.001).
Conclusion: The experiences of different symptoms by children and adolescents who receive HSCT must be considered. In addition, nursing interventions, such as self-help meetings with peer groups, should be provided to improve their HRQoL.
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Adolescent; Child; Hematopoietic stem cell transplantation; Quality of life
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