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Associations between bone mineral density, trabecular bone score, and body mass index in postmenopausal females

Osteoporosis and Sarcopenia 2020년 6권 3호 p.111 ~ 114
Shayganfar Azin, Farrokhi Mehrdad, Shayganfar Sanaz, Ebrahimian Shadi,
소속 상세정보
 ( Shayganfar Azin ) - Isfahan University of Medical Sciences School of Medicine Department of Radiology
 ( Farrokhi Mehrdad ) - Isfahan University of Medical Sciences School of Medicine
 ( Shayganfar Sanaz ) - Isfahan University of Medical Sciences School of Medicine Department of Radiology
 ( Ebrahimian Shadi ) - Isfahan University of Medical Sciences School of Medicine Department of Radiology

Abstract


Objectives: Bone mineral density (BMD), as a gold standard determinant of osteoporosis, assesses only one of many characteristics contributing to the bone. Trabecular bone score (TBS) is applied to evaluate the microarchitecture of trabecular bone. A high body mass index (BMI) has been reported to have a positive correlation with BMD. However, the relation between BMI and TBS has remained unclear. Therefore, the aim of this study is to shed light on the associations between BMI, T-score, and TBS in postmenopausal women without a diagnosed underlying disease.

Methods: In this cross-sectional study, 1054 postmenopausal women were randomly recruited from the Department of Radiology, Isfahan University of Medical Sciences. Demographic characteristics and medical history of all subjects were collected from documents. TBS measurements for L1-L4 vertebrae were retrospectively performed by the TBS iNsight software using the dual X-ray absorptiometry (DXA) from the same region of spine of the subjects. The analysis was done to detect the correlation between TBS and BMI.

Results: A statistically significant negative correlation was found between TBS and BMI in patients with osteoporosis and low bone mass. In patients with normal T-scores, BMI was not significantly correlated to TBS (P > 0.05). Furthermore, there was a significant positive association between T-score and BMI.

Conclusions: Although a higher BMI had a protective effect against osteoporosis, higher BMI was associated with a lower TBS in patients with an abnormal T-score. However, BMI did not have a significant effect on TBS in patients with normal T-scores.

키워드

Bone mineral density; Trabecular bone score; Body mass index

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