잠시만 기다려 주세요. 로딩중입니다.

The Effectiveness of Acupuncture Treatment for Patients with Alzheimer’s Disease: A Meta-Analysis of Randomized Controlled Trials

Journal of Acupuncture Research 2020년 37권 4호 p.209 ~ 223
신진현, 신혜정, 김의별, 안윤영, 육태한, 최유민, 송범용, 김종욱,
소속 상세정보
신진현 ( Shin Jin-Hyeon ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine
신혜정 ( Shin Hye-Jeong ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine
김의별 ( Kim Eui-Byeol ) - Woosuk University Korean Medicine Hospital Department of Rehabilitation Medicine of Korean Medicine
안윤영 ( An Yun-Young ) - Woosuk University College of Korean Medicine Department of Neuropsychiatry
육태한 ( Yook Tae-Han ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine
최유민 ( Choi Yoo-Min ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine
송범용 ( Song Beom-Yong ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine
김종욱 ( Kim Jong-Uk ) - Woosuk University Korean Medicine Hospital Department of Acupuncture and Moxibustion Medicine

Abstract


The purpose of this study was to evaluate the effectiveness of acupuncture treatment for the symptoms of Alzheimer’s disease (AD). There were 11 databases searched for randomized controlled trials using acupuncture treatment for AD. The risk-of-bias assessment tool of the Cochrane Library was used to evaluate the quality of each study. Using the Review Manager (RevMan), a meta-analysis was performed using risk ratio, mean difference, 95% confidence interval, and random effect model. There were 32 studies selected, all of which were conducted in China. There were 16 studies where acupuncture was used as the intervention, and 23 studies used Donepezil as the control group. Acupoint GV20 was most frequently selected during the treatment. The Mini Mental State Examination (MMSE) was the most frequently used outcome variable. A period of 12 weeks was the most common treatment duration. As a result of meta-analysis (n = 25), acupuncture improved the MMSE and activities of daily living scores. Electroacupuncture improved the Alzheimer Disease Assessment Scale-Cognitive Subscale, and scalp acupuncture improved the MMSE score for AD. Acupuncture alleviates the symptoms of AD. However, further research is necessary to provide a better level of evidence.

키워드

Alzheimer disease; acupuncture; cognition disorders; activities of daily living; meta-analysis

원문 및 링크아웃 정보

등재저널 정보