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Ultra-widefield Fluorescein Angiography Findings in Patients with Multiple Retinal Holes

Journal of Retina 2020³â 5±Ç 2È£ p.122 ~ 127
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¹ÚÁøÇü ( Park Jin-Heung ) - Keye Eye Center
¾çÇöŹ ( Yang Hyeon-Tak ) - Keye Eye Center
¹éÁö¿ø ( Baek Ji-Won ) - Catholic University College of Medicine Bucheon St. Mary¡¯s Hospital Department of Ophthalmology
Àü¼ÒÈñ ( Jeon So-Hee ) - Keye Eye Center

Abstract


Purpose: To evaluate ultra-widefield fluorescein angiography (UWFA) findings in patients with multiple retinal holes.

Methods: UWFA findings were compared between 73 eyes with more than two retinal holes and 39 age-matched controls. Factors associated with a high score were evaluated.

Results: Patients with multiple retinal holes showed a significantly higher prevalence of abnormal UWFA findings, such as Angiography Scoring for Uveitis Working Group (ASUWG) retinal vascular staining/leakage and capillary leakage at the posterior pole, and peripheral capillary leakage (p < 0.001 for all). Univariate analysis revealed that spherical equivalent (r = -0.336, p = 0.005) and number of retinal holes (r = 0.267, p = 0.023) were associated with a higher ASUWG score. Multivariate regression analysis revealed that the spherical equivalent was independently associated with a higher ASUWG score (r2 = 0.113, p = 0.005). Vitreous tractions were detected by optical coherence tomography on the edge of retinal holes in these patients.

Conclusions: Eyes with strong focal adhesion between the vitreous cortex and the inner retinal surface could develop dye leakages and multiple retinal holes.

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High myopia; Retinal hole; Rhegmatogenous retinal detachment; Ultra-wide-field fluorescein angiography; Vitreoretinal adhesion

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