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전립샘비대증 발생에 미치는 대사 요인의 영향: 국민건강보험공단자료를 이용하여

Metabolic Factors Associated with Incidence of Benign Prostatic Hyperplasia in Korea: Using National Health Insurance Service Data

보건정보통계학회지 2020년 45권 4호 p.418 ~ 425
고태화, 김혜심, 강대용, 정재흥, 권성원, 김세철, 송재만, 정현철, 고상백,
소속 상세정보
고태화 ( Go Tae-Hwa ) - Yonsei University Wonju College of Medicine Department of Biostatistics
김혜심 ( Kim Hye-Sim ) - Yonsei University Wonju College of Medicine Artificial Intelligence BigData Medical Center
강대용 ( Kang Dae-Ryong ) - Yonsei University Wonju College of Medicine Department of Precision Medicine
정재흥 ( Jung Jae-Hung ) - Yonsei University Wonju College of Medicine Department of Urology
권성원 ( Kwon Sung-Won ) - Korea Prostate Health Council
김세철 ( Kim Sae-Chul ) - Korea Prostate Health Council
송재만 ( Song Jae-Mann ) - Korea Prostate Health Council
정현철 ( Chung Hyun-Chul ) - Yonsei University Wonju College of Medicine Department of Urology
고상백 ( Koh Sang-Baek ) - Yonsei University Wonju College of Medicine Department of Preventive Medicine

Abstract


Objectives: To investigate the effect of metabolic factors on benign prostatic hyperplasia (BPH) by age in Korean men.

Methods: This study confirmed the occurrence of BPH from 2013 to 2017 in men over 40 years of age who had undergone general health checkups from 2009 to 2010 using the National Health Insurance Corporation data. They were divided into 10-year-olds from 40s to 80s or over, and the effect of BMI and waist circumference on BPH was confirmed using the Cox proportional hazard model.

Results: As a result of the analysis, in the 40s and 50s, the effect of BMI on BPH was not statistically significant. However, in the 60s, 70s, and 80s or over, the risk of BPH incidence was 1.41 times, 1.22 times, and 3.01 times, respectively, in obese people compared to underweight. In addition, waist circumference had a statistically significant effect on BPH in all age groups except for the 40s. As a result of analysis of hypertension, diabetes, and hyperlipidemia, the risk of BPH was higher in the group compared to the group without a history, but as a result of analyzing by age group, statistically significant results were found only in the 50s and 60s.

Conclusions: Metabolic factors such as obesity, hypertension, diabetes mellitus, and hyperlipidemia was associated with the incidence of BPH. To improve quality of life in elderly, the management plan for metabolic factors should be considered.

키워드

Benign prostatic hyperplasia; Metabolic factors; Risk factors

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