Characterization of Venous Involvement in Vasculo-Behcet Disease
이나현, 배미주, 진모란, 정성운, 이충원, 전창호,
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이나현 ( Lee Na-Hyeon ) - Pusan National University School of Medicine Pusan National University Hospital Department of Thoracic and Cardiovascular Surgery
배미주 ( Bae Mi-Ju ) - Pusan National University School of Medicine Pusan National University Hospital Department of Thoracic and Cardiovascular Surgery
진모란 ( Jin Mo-Ran ) - Pusan National University School of Medicine Pusan National University Hospital Department of Thoracic and Cardiovascular Surgery
정성운 ( Chung Sung-Woon ) - Pusan National University School of Medicine Pusan National University Hospital Department of Thoracic and Cardiovascular Surgery
이충원 ( Lee Chung-Won ) - Pusan National University School of Medicine Pusan National University Hospital Department of Thoracic and Cardiovascular Surgery
전창호 ( Jeon Chang-Ho ) - Pusan National University School of Medicine Pusan National University Hospital Department of Radiology
Abstract
Background: Behcet disease is a chronic inflammatory disorder with a varying etiology. Herein, we report the involvement of peripheral veins in Behcet disease and discuss the treatment thereof.
Methods: Thirty-four patients with venous involvement in vasculo-Behcet disease were retrospectively analyzed over 15 years. We reviewed the clinical manifestations, treatment choices, and complications of these patients.
Results: Deep vein thrombosis (DVT) was observed in 24 patients (70.59%) and varicose veins in 19 (52.94%). Immunosuppressive treatment was administered to all patients due to the pathological feature of vein wall inflammation. In patients with DVT, anticoagulation therapy was also used, but post-thrombotic syndrome was observed in all patients along with chronic luminal changes. Eleven patients with isolated varicose veins underwent surgery; although symptoms and lesions recurred in half of these patients, no cases of secondary DVT occurred.
Conclusion: When DVT was diagnosed in patients with Behcet disease, there was no cure for the lesions. Ultrasonographic abnormalities were observed in all patients, and post-thrombotic syndrome remained to varying degrees. In cases of isolated varicose veins in patients with Behcet disease, DVT did not occur after surgical treatment. If the activity of Behcet disease is controlled, surgical correction of varicose veins is preferable.
키워드
Behcet syndrome; Venous thrombosis; Thrombophlebitis
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