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Hypoglycemic, antistress, anxiolytic, and nootropic activity of roots of Rubia cordifolia Linn

Oriental Pharmacy and Experimental Medicine 2004년 4권 4호 p.235 ~ 242
Kasture Veena S., Kasture Sanjay B.,
소속 상세정보
 ( Kasture Veena S. ) - College of Pharmacy Natural Products Laboratory
 ( Kasture Sanjay B. ) - College of Pharmacy Natural Products Laboratory

Abstract


The alcoholic extract of dried roots of Rubia cordifolia dose dependently reduced blood sugar level in alloxan treated rats. The extract also reduced ulcer index, plasma corticosterone in cold restrain stressed rats in dose related manner. The mice treated with alcoholic extract of Rubia cordifolia spent more time in the open arm of the elevated plus maze indicating anxiolytic activity. The extract also antagonized the amnesic effect of scopolamine in mice as indicated by reduced transfer latency in the elevated plus maze. Thus the plant bears potential for use in diabetes, stress, anxiety, and dementia.

키워드

Rubia cordifolia;Hypoglycemic;Anxiolytic;Antistress;Nootropic

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