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Economic Burden of Periprosthetic Joint Infection Following Primary Total Knee Replacement in a Developing Country

Clinics in Orthopedic Surgery 2020년 12권 4호 p.470 ~ 476
Iqbal Faizan, Shafiq Bilal, Noor Syed Shahid, Ali Zulfiqar, Memon Nouman, Memon Naveed,
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 ( Iqbal Faizan ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery
 ( Shafiq Bilal ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery
 ( Noor Syed Shahid ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery
 ( Ali Zulfiqar ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery
 ( Memon Nouman ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery
 ( Memon Naveed ) - Liaquat National Hospital and Medical College Department of Orthopedic Surgery

Abstract


Background: Periprosthetic joint infection is one of the devastating complications after primary total knee arthroplasty, which increases the financial burden on patients and affects their quality of life as well. The financial burden of periprosthetic joint infection after joint replacement in developed countries is well known. There is a need to evaluate the economic burden in developing countries such as Pakistan.

Methods: This is a single-center, retrospective, case-control study conducted at the Department of Orthopedic Surgery, Liaquat National Hospital Karachi. Cases of primary total knee arthroplasty performed during this study were divided into 2 groups: uneventful primary total knee arthroplasty and periprosthetic joint infection treated with 2-stage revision. To calculate the final cost, we divided the total hospital cost into the hospital stay cost and operating room cost.

Results: During study period, 32 patients were diagnosed with periprosthetic joint infection. The total cost of revision surgery for periprosthetic joint infection considering 2 hospitalizations was 1,780,222 ± 313,686 Pakistani rupee (PKR). The total cost of uneventful arthroplasty was 390,172 ± 51,460 PKR. We observed significant difference with respect to economic details between the 2 groups.

Conclusions: Management of periprosthetic joint infection was 4.5 times more expensive than uneventful primary total knee arthroplasty. Measures should be undertaken to reduce the prevalence of periprosthetic joint infection, thereby reducing patients' economic burden.

키워드

Total knee arthroplasty; Periprosthetic joint infection; Economic burden; Revision surgery

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