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Cryosurgery as a Minimally Invasive Alternative Treatment for a Patient with Erosive Adenomatosis of the Nipple

Annals of Dermatology 2021년 33권 2호 p.182 ~ 185
배경남, 신기혁, 김우일, 양민영, 이원구, 김훈수, 고현창, 김병수, 김문범, 김건욱,
소속 상세정보
배경남 ( Bae Kyung-Nam ) - Pusan National University School of Medicine Department of Dermatology
신기혁 ( Shin Ki-Hyuk ) - Pusan National University School of Medicine Department of Dermatology
김우일 ( Kim Woo-Il ) - Pusan National University School of Medicine Department of Dermatology
양민영 ( Yang Min-Young ) - Pusan National University School of Medicine Department of Dermatology
이원구 ( Lee Won-Ku ) - Pusan National University School of Medicine Department of Dermatology
김훈수 ( Kim Hoon-Soo ) - Pusan National University School of Medicine Department of Dermatology
고현창 ( Ko Hyun-Chang ) - Pusan National University School of Medicine Department of Dermatology
김병수 ( Kim Byung-Soo ) - Pusan National University School of Medicine Department of Dermatology
김문범 ( Kim Moon-Bum ) - Pusan National University School of Medicine Department of Dermatology
김건욱 ( Kim Gun-Wook ) - Dong-A University College of Medicine Department of Dermatology

Abstract


Erosive adenomatosis of the nipple (EAN), also known as nipple adenoma, florid papillomatosis, or papillary adenoma of the nipple, is a benign neoplasm originating from a lactiferous duct of the breast. Although the potential for malignant change is invariably negligible, the nature of the disease is quite intractable despite several treatment methods. Surgical excision is known as the treatment of choice, but this invasive approach is generally not acceptable to the vast majority of patients due to the cosmetic outcomes. Cryosurgery could be an alternative choice to preserve the structure of the nipple-areola complex, though its application has not been studied due to the paucity of cases. A 22-year-old female presented with a unilateral, crater-like erosion of the left nipple with serosanguineous discharge. The skin biopsy revealed proliferation of tubular structures, which corresponded to EAN. She was treated with 4 sessions of cryosurgery (open cryospray with liquid nitrogen) over 6 months, and the skin lesion resolved completely without any recurrence for 12 months. Although further study is required to determine the optimal treatment regimen for EAN, cryosurgery should be considered as an effective option to surgical excision.

키워드

Apocrine glands; Cryosurgery; Erosive adenomatosis of the nipple

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